Article

TM-Loop: Transformer Multi-omics Hierarchical detection of chromatin Loop

2026-03-24

Abstract excerpt

<title>Abstract</title> <p>Background Chromatin loops form the hierarchical 3D genome architecture and act as critical regulatory hubs, bringing distant cis-elements together to precisely control target gene transcription. Disruption of these spatial interactions is closely linked to human diseases including cancer. Hi-C provides genome-wide interaction maps, yet robust identification of chromatin loops remains...

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Literature Corpus work: b99a8a36-cc56-5444-9cc8-8ebd7bde0a30
DOI: 10.21203/rs.3.rs-9074068/v1

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