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Article

Mutations in m6A consensus motifs are suppressed in the m6A modified genes in human cancer cells.

PloS one - 1 Jan 2020

An Mingzi, Wang Huiyun, Zhu Yingqian

Abstract excerpt

N6-methyladenosine (m6A) is the most prevalent type of RNA modification. METTL3 in the methyltransferase complex is the core enzyme responsible for methylation. METTL3 selectively catalyzes the adenosines centered in the RRAC motif. Functional studies established that m6A could enhance the translation efficiency (TE) of modified genes by recruiting reader protein YTHDF1 and other initiation factors. We downloaded...

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PMID: 32790688
DOI: 10.1371/journal.pone.0236882
PMCID: PMC7425885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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