Article

Expansion of RNA sequence diversity and RNA editing rates throughout human cortical development

2021-06-10

Abstract excerpt

<h4>ABSTRACT</h4> Post-transcriptional modifications by RNA editing are essential for neurodevelopment, yet their developmental and regulatory features remain poorly resolved. We constructed a full temporal view of base-specific RNA editing in the developing human cortex, from early progenitors through fully mature cells found in the adult brain. Developmental regulation of RNA editing is characterized by an incr...

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Literature Corpus work: 8de59845-2731-5bdd-80da-165e2bdf2492
DOI: 10.1101/2021.06.10.447947

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