Article

Isoform-level profiling of m6A epitranscriptomic signatures in human brain

2024-01-31

Abstract excerpt

<h4>ABSTRACT</h4> The RNA modification N6-methyladenosine (m6A) is highly abundant in the human brain and implicated in neuropsychiatric and neurodegenerative disorders. However, most techniques for studying m6A cannot resolve modifications within RNA isoforms and we lack an isoform-level map of m6A sites in the brain. Profiling m6A within isoforms is therefore a critical step towards understanding the complex me...

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Literature Corpus work: cd47c0b1-5ca9-5023-9078-c4f3d2a1cfed
DOI: 10.1101/2024.01.31.578088

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