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Article

The dynamic epitranscriptome: A to I editing modulates genetic information

6 Jul 2015

Abstract excerpt

Adenosine to inosine editing (A to I editing) is a cotranscriptional process that contributes to transcriptome complexity by deamination of adenosines to inosines. Initially, the impact of A to I editing has been described for coding targets in the nervous system. Here, A to I editing leads to recoding and changes of single amino acids since inosine is normally interpreted as guanosine by cellular machines....

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PMID: 26148686
DOI: 10.1007/s00412-015-0526-9

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