Article

The regulation of Insulin/IGF-1 signaling by miR-142-3p associated with human longevity

2023-05-20

Abstract excerpt

MicroRNAs (miRNAs) have been demonstrated to modulate life span in the invertebrates C. elegans and Drosophila by targeting conserved pathways of aging, such as insulin/IGF-1 signaling (IIS). However, a role for miRNAs in modulating human longevity has not been fully explored. Here we investigated novel roles of miRNAs as a major epigenetic component of exceptional longevity in humans. By profiling the miRNAs in...

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Literature Corpus work: b80d5385-0aca-5330-b7d6-b29ab3f20d60
DOI: 10.1101/2023.05.19.541542

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