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Article

Circulating microRNA profile in humans and mice with congenital GH deficiency

12 Jun 2021

Abstract excerpt

Reduced inflammation, increased insulin sensitivity, and protection against cancer are shared between humans and mice with GH/IGF1 deficiency. Beyond hormone levels, miRNAs are important regulators of metabolic changes associated with healthy aging. We hypothesized that GH deficiency in humans alters the abundance of circulating miRNAs and that a subset of those miRNAs may overlap with those found in GH-deficient...

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PMID: 34118183
DOI: 10.1111/acel.13420

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