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Article

Role of insulin/insulin-like growth factor 1 signaling pathway in longevity

1 Jan 2005

Abstract excerpt

The insulin/insulin-like growth factor 1 (IGF-1) signaling pathway is evolutionary conserved in diverse species including C.elegans, saccharomyces cerevisiae, Drosophila melanogaster, rodents and humans, which is involved in many interrelated functions that are necessary for metabolism, growth and reproduction. Interestingly, more and more research has revealed that insulin/IGF-1 signaling pathway plays a pivotal...

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PMID: 15800976
DOI: 10.3748/wjg.v11.i13.1891

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