Article

Enhanced lentiviral gene delivery to mammalian cells via paired cell surface and viral envelope engineering

2024-11-11

Abstract excerpt

<h4>ABSTRACT</h4> Lentiviral vectors that facilitate gene delivery to desired cell types have been widely used in routine laboratory research and therapeutic cell engineering. However, the lack of proper entry receptors on many cell types often results in poor gene delivery. Here, we present a simple paired virus-cell engineering approach that promotes lentiviral gene delivery into mammalian cells. Lentiviruses a...

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Identifiers and source

Literature Corpus work: b8091ccb-3791-55e5-a914-b6517fac37aa
DOI: 10.1101/2024.11.08.622723

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