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Programmable enveloped delivery vehicles for human genome engineering <i>in vivo</i>

2022-08-24

Abstract excerpt

Viruses and virally-derived particles have the intrinsic capacity to deliver molecules to cells, but the difficulty of readily altering cell-type selectivity has hindered their use for therapeutic delivery. Here we show that cell surface marker recognition by antibody fragments displayed on membrane-derived particles encapsulating CRISPR-Cas9 protein and guide RNA can target genome editing tools to specific cells....

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Identifiers and source

Literature Corpus work
0082c47c-845c-5f35-86c8-b5d76740f557
DOI
10.1101/2022.08.24.505004
Open publication

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Programmable enveloped delivery vehicles for human genome engineering <i>in vivo</i>DOI 10.1101/2022.08.24.505004
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