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Surface-Engineered Lentiviral Vectors for Selective Gene Transfer into Subtypes of Lymphocytes

16 Oct 2018

Abstract excerpt

Lymphocytes have always been among the prime targets in gene therapy, even more so since chimeric antigen receptor (CAR) T cells have reached the clinic. However, other gene therapeutic approaches hold great promise as well. The first part of this review provides an overview of current strategies in lymphocyte gene therapy. The second part highlights the importance of precise gene delivery into B and T cells as...

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PMID: 30417026
DOI: 10.1016/j.omtm.2018.10.006

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