Article

GET: a foundation model of transcription across human cell types

2023-09-24

Abstract excerpt

Transcriptional regulation, involving the complex interplay between regulatory sequences and proteins, directs all biological processes. Computational models of transcription lack generalizability to accurately extrapolate in unseen cell types and conditions. Here, we introduce GET, an interpretable foundation model designed to uncover regulatory grammars across 213 human fetal and adult cell types. Relying exclus...

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Literature Corpus work: b66146f0-a83f-5989-9e0b-eefe1be191c4
DOI: 10.1101/2023.09.24.559168

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