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A high-resolution atlas of cattle regulatory variants and their cross-species activity in matched human cells

2026-05-07

Abstract excerpt

Identifying causal noncoding variants underlying complex traits in cattle remains challenging because high-resolution functional maps of regulatory variation are lacking. Here we combine massively parallel reporter assays with graph genomics to measure autonomous transcriptional activity from >1.5 billion DNA fragments spanning both cattle subspecies. In primary bovine cells, we assay >15 million variants and iden...

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Literature Corpus work
197189ff-6ad7-5aeb-ab69-95d8592bf36d
DOI
10.64898/2026.05.06.723179
Open publication

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A high-resolution atlas of cattle regulatory variants and their cross-species activity in matched human cellsDOI 10.64898/2026.05.06.723179
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