Article

Biases introduced by Ficoll-based isolation in acute myeloid leukemia sample analyses support the use of hemolysis

2026-02-12

Abstract excerpt

<h4>ABSTRACT</h4> Acute myeloid leukemia (AML) is a heterogeneous malignancy whose characterization relies on immunophenotyping and molecular profiling. While hemolysis is recommended for leukocyte isolation in clinical diagnostics, Ficoll-based density gradient centrifugation is widely used in research and biobanking. Here, we evaluated the impact of Ficoll isolation on commonly performed analyses of AML samples...

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Literature Corpus work: b64f1e6b-9f57-5f3c-8894-0955572e8d82
DOI: 10.64898/2026.02.11.705243

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