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Evaluation of automatic cell free DNA extraction metrics using different blood collection tubes

3 Jun 2025

Abstract excerpt

Abstract Liquid biopsies and cell-free DNA (cfDNA) analysis are used in numerous clinical applications. The amount of cfDNA is generally limited and many approaches require assessment of individual molecules. Optimized pre-analytical steps are therefore fundamental for accurate interpretation. Here, we established an automated extraction approach providing cfDNA of high yield and quality. We analyzed 649 blood...

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PMID: 40461680
DOI: 10.1038/s41598-025-03508-4

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