Article

Functional and transcriptional heterogeneity of the human haematopoietic stem cell pool at steady-state and under inflammation

2021-01-01

Abstract excerpt

Blood production is coordinated by a functionally heterogeneous pool of multipotent haematopoietic stem cells (HSCs), downstream of which lineage-restricted progenitors are generated. The advent of single cell technologies has changed our view of the haematopoiesis to a dynamic continuum. Understanding the early differentiation trajectories of HSCs, and how environment and molecular factors can modify them, is vit...

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Literature Corpus work: 940d8f7e-6602-5ac0-a6d1-f77c9cf215f0
DOI: 10.17863/cam.65284

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