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CD200 expression marks leukemia stem cells in human AML

4 Nov 2020

Abstract excerpt

The leukemia stem cell (LSC) populations of acute myeloid leukemia (AML) exhibit phenotypic, genetic, and functional heterogeneity that contribute to therapy failure and relapse. Progress toward understanding the mechanistic basis for therapy resistance in LSCs has been hampered by difficulties in isolating cell fractions that enrich for the entire heterogeneous population of LSCs within individual AML samples....

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PMID: 33147339
DOI: 10.1182/bloodadvances.2020001802

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