Article

Multivariate genome-wide analyses of insulin resistance phenotypes unravel novel loci and therapeutic targets for cardiometabolic health and longevity

2025-06-10

Abstract excerpt

<title>Abstract</title> <p>Insulin resistance (IR) is a key risk factor for cardiometabolic diseases and premature death with unmet therapeutic needs. The limited identification of IR-associated loci hinders understanding its causal role in cardiometabolic health and longevity, impeding subsequent precise therapeutic strategies development. We applied three complementary multivariate genome-wide association study...

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Literature Corpus work: b5d2b316-2e06-51f4-9d61-3dede41f2f64
DOI: 10.21203/rs.3.rs-6768173/v1

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