Article

Unraveling The Mystery of Insulin Resistance: From Principle Mechanistic Insights and Consequences to Therapeutic Interventions

2025-02-24

Abstract excerpt

Insulin resistance (IR) is a significant factor in the development and progression of metabolic-related diseases like dyslipidemia, T2DM, hypertension, nonalcoholic fatty liver disease, cardiovascular and cerebrovascular disorders and cancer. The pathogenesis of IR depends on multiple factors including age, genetic predisposition, obesity, oxidative stress and other factors. Abnormalities in the insulin signaling...

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Literature Corpus work: a1dda728-1d62-55a4-b88e-201a0c1f8aae
DOI: 10.20944/preprints202502.1814.v1

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