Article
Insulin resistance-related indices, genetic risk, and the risk of cardiovascular disease in individuals with preclinical or clinical obesity: a large prospective cohort study in the UK biobank.
Cardiovascular diabetology - 25 Oct 2025
Hu Jinling, Shang Cong, Huang Yueqing, Sun Chaonan, Zhang Jing
Abstract excerpt
BACKGROUND: Insulin resistance (IR)-related indices are validated prognostic markers in metabolic disorders, but have not been applied to preclinical or clinical obesity. This study aimed to investigate the relationship between IR-related indices and cardiovascular disease (CVD) incidence, considering genetic factors and biomarkers. METHODS: This prospective study analyzed 112,866 UK Biobank participants with...
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- Humans
- Prospective Studies
- Male
- Female
- Middle Aged
- United Kingdom