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Article

Multi-tissue transcriptome-wide association study reveals susceptibility genes and drug targets for insulin resistance-relevant phenotypes.

Diabetes, obesity & metabolism - 1 Jan 2024

Duan Yuan-Yuan, Ke Xin, Wu Hao, Yao Shi, Shi Wei, Han Ji-Zhou, Zhu Ren-Jie, Wang Jia-Hao, Jia Ying-Ying, Yang Tie-Lin, Li Meng, Guo Yan

Abstract excerpt

AIM: Genome-wide association studies (GWAS) have identified multiple susceptibility loci associated with insulin resistance (IR)-relevant phenotypes. However, the genes responsible for these associations remain largely unknown. We aim to identify susceptibility genes for IR-relevant phenotypes via a transcriptome-wide association study. MATERIALS AND METHODS: We conducted a large-scale multi-tissue...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37779362
DOI: 10.1111/dom.15298

Genes

CACNB2
DRD2
H6PD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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