Article

Airqtl dissects cell state-specific causal gene regulatory networks with efficient single-cell eQTL mapping

2025-01-17

Abstract excerpt

Single-cell expression quantitative trait loci (sceQTL) mapping offers a powerful approach for understanding gene regulation and its heterogeneity across cell types and states. It has profound applications in genetics and genomics, particularly causal gene regulatory network (cGRN) inference to unravel the molecular circuits governing cell identity and function. However, computational scalability remains a critica...

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Literature Corpus work: 1f0d5a18-c250-519e-b37f-c9e6f0d86c04
DOI: 10.1101/2025.01.15.633041

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