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Article

Resident Memory-like CD8+ T Cells Are Involved in Chronic Inflammatory and Neurodegenerative Diseases in the CNS.

Neurology(R) neuroimmunology & neuroinflammation - 1 Jan 2024

Kimura Kimitoshi, Nishigori Ryusei, Hamatani Mio, Sawamura Masanori, Ashida Shinji, Fujii Chihiro, Takata Masaki, Lin Youwei, Sato Wakiro, Okamoto Tomoko, Kuzuya Akira, Takahashi Ryosuke, Yamamura Takashi, Kondo Takayuki

Abstract excerpt

BACKGROUND AND OBJECTIVES: Resident memory T (Trm) cells are a unique population that can survive and function in a compartmentalized tissue with inflammatory potential. We aim to investigate the alteration of Trm population in acute/chronic inflammatory and neurodegenerative diseases in the CNS. METHODS: The frequencies of CD4+ and CD8+ T cells expressing both CD69 and CD103, the markers for Trm cells, were...

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Identifiers

PMID: 37949669
DOI: 10.1212/NXI.0000000000200172
PMCID: PMC10691221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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