Article

Meta-Prediction of Coronary Artery Disease Risk

2023-12-20

Abstract excerpt

<title>Abstract</title> <p>Coronary artery disease (CAD) remains the leading cause of mortality and morbidity worldwide. Recent advances in large-scale genome-wide association studies have highlighted the potential of genetic risk, captured as polygenic risk scores (PRS), in clinical prevention. However, the current clinical utility of PRS models is limited to identifying high-risk populations based on the top pe...

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Literature Corpus work: b547200a-b5f3-5681-845c-d6e3908074dc
DOI: 10.21203/rs.3.rs-3694374/v1

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