Article

The metabolite α-ketobutyrate increases health and life spans by activating AMPK

2022-10-13

Abstract excerpt

Aging is a complex process that is directly related to human health and disease. The extraordinary finding that aging is malleable, as shown in model organisms whose life and health spans are extended by specific gene mutations or dietary or pharmacological perturbations 1–3 , has offered enormous hope for our understanding and treatment of aging and related diseases. Although many molecules have been identified...

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Literature Corpus work: b45aa2a3-2d6d-524e-960d-22188c2ad48f
DOI: 10.1101/2022.10.10.511641

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