Article

ZHX2 alleviates vascular remodeling and smooth muscle cell proliferation by transcriptional regulation of GADD45G

2023-10-16

Abstract excerpt

<h4>Objective</h4> This study explores the role of ZHX2 in vascular remodeling, specifically focusing on its effects on VSMC proliferation, migration, and neointima formation following vascular injury. <h4>Methods and Results:</h4> Data from both human atherosclerotic samples and a mouse carotid injury model indicated a decrease in ZHX2 levels. In vivo , ZHX2 overexpression reduced neointima formation in mice su...

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Literature Corpus work: b4445001-c4b1-5876-88ac-c33e6c7ed087
DOI: 10.1101/2023.10.15.562431

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