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Article

Spatial Transcriptomics Reveals Region-Specific Remodeling in Vein Grafts After Peripheral Arterial Bypass

2026-06-11

Abstract excerpt

<h4>Background</h4> Vein graft failure due to intimal hyperplasia and maladaptive remodeling remains a major limitation of peripheral bypass surgery. Although vascular remodeling is recognized as a multilayered process, layer-specific molecular mechanisms that distinguish adaptive from negative remodeling remain incompletely understood. We aimed to investigate the vascular microenvironment of patent and stenotic...

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Literature Corpus work
7608a778-d6e2-54df-82c6-848711b99d49
DOI
10.64898/2026.06.08.731009
Open publication

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