Article

NuRD independent Mi-2 activity represses ectopic gene expression during neuronal maturation

2022-04-19

Abstract excerpt

During neuronal development, extensive changes to chromatin states occur to regulate lineage-specific gene expression. The molecular factors underlying the repression of non-neuronal genes in differentiated neurons are poorly characterised. The Mi2/NuRD complex is a multiprotein complex with nucleosome remodelling and histone deacetylase activity. Whilst NuRD has previously been implicated in the development of ne...

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Literature Corpus work: b297aa5c-c8d1-5ed9-b98d-838b6e12c012
DOI: 10.1101/2022.04.19.488642

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