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NEUROD1: transcriptional and epigenetic regulator of human and mouse neuronal and endocrine cell lineage programs

22 Jul 2024

Abstract excerpt

Transcription factors belonging to the basic helix-loop-helix (bHLH) family are key regulators of cell fate specification and differentiation during development. Their dysregulation is implicated not only in developmental abnormalities but also in various adult diseases and cancers. Recently, the abilities of bHLH factors have been exploited in reprogramming strategies for cell replacement therapy. One such...

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PMID: 39105169
DOI: 10.3389/fcell.2024.1435546

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