Article

Transcriptional Mapping of Neuro-Immune Interactions during Homeostasis and HIV infection using Microglia-containing Human Cerebral Assembloids

2026-08-10

Abstract excerpt

<h4>Background</h4> A significant number of people with HIV-1 still experience neurocognitive impairments (NCI), despite effective antiretroviral treatment. HIV-NCI is diverse and multifactorial, with mechanisms that cause its development and progression still not fully understood. We examined early HIV-related changes in brain stability and studied neuroimmune interactions at the single-cell level to better unde...

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Literature Corpus work: b2970ac7-abac-5536-ac92-ea042864efea
DOI: 10.64898/2026.08.10.743763

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