Article

HIV-1 infection of human microglia activates inflammatory pathways associated with HIV-associated neurocognitive disorders (HAND)

2025-02-13

Abstract excerpt

HIV-associated neurocognitive disorders (HAND) cause significant dysfunction among people living with HIV. Microglia are the primary immune cells of the central nervous system and are readily infected by HIV. Microglia are thought to contribute to neuroinflammation and cognitive dysfunction in neurodegenerative diseases such as Alzheimer’s Disease and are likely to play an important role in the pathogenesis of HAN...

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Literature Corpus work: b5096a3d-32b7-5b8b-bf79-5c0ce1234e5e
DOI: 10.1101/2025.02.13.638028

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