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Article

Human microglial models to study HIV infection and neuropathogenesis: a literature overview and comparative analyses

1 Feb 2022

Abstract excerpt

HIV persistence in the CNS despite antiretroviral therapy may cause neurological disorders and poses a critical challenge for HIV cure. Understanding the pathobiology of HIV-infected microglia, the main viral CNS reservoir, is imperative. Here, we provide a comprehensive comparison of human microglial culture models: cultured primary microglia (pMG), microglial cell lines, monocyte-derived microglia (MDMi), stem...

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HIV-related health complications and treatments
HIV Research and Treatment
Neuroinflammation and Neurodegeneration Mechanisms

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35138593
DOI: 10.1007/s13365-021-01049-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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