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Modeling HIV-1 infection and NeuroHIV in hiPSCs-derived cerebral organoid cultures

10 Apr 2024

Abstract excerpt

The human immunodeficiency virus (HIV) epidemic is an ongoing global health problem affecting 38 million people worldwide with nearly 1.6 million new infections every year. Despite the advent of combined antiretroviral therapy (cART), a large percentage of people with HIV (PWH) still develop neurological deficits, grouped into the term of HIV-associated neurocognitive disorders (HAND). Investigating the...

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PMID: 38600307
DOI: 10.1007/s13365-024-01204-z

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