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Investigation of CNS damage following HIV infection and methamphetamine exposure using human iPSC-derived microglia and 3D cerebral assembloid models

2025-12-10

Abstract excerpt

<h4>ABSTRACT</h4> HIV-associated neurocognitive disorder (HAND) is characterized by glial activation and neuroinflammation emerging from HIV infection. Moreover, methamphetamine (METH) is a highly addictive psychostimulant whose use is linked to high HIV prevalence, significantly worsening clinical outcomes for people living with HIV and hastening onset of systemic illness. Overall, pathologies associated with HI...

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Literature Corpus work
a52f5676-bb3e-59d7-bf76-71a007e01174
DOI
10.64898/2025.12.06.692767
Open publication

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