Article
L1 retrotransposition is regulated post-transcriptionally In High-Grade Serous Ovarian Cancer
2022-09-28
Abstract excerpt
L1 retrotransposons are the only protein-coding active transposable elements in the human genome. Although silenced during normal conditions, they are highly expressed in human epithelial cancers including high-grade serous ovarian cancer (HGSC), where they transcribe to form L1 mRNA and subsequently integrate into the genome by a process called retrotransposition. Despite of high L1 protein expression in the earl...
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Identifiers and source
- Literature Corpus work
- b28edc7c-6edc-5926-a3cd-56a74a1f925f
- DOI
- 10.1101/2022.09.27.509826