Article

Upregulation of adenosine A2A receptor by astrocytes is sufficient to trigger hippocampal multicellular dysfunctions and memory deficits.

2024-08-26

Abstract excerpt

<title>Abstract</title> Adenosine is an ubiquitous neuromodulator that ensures cerebral homeostasis. It exerts numerous functions through the activation of G-protein-coupled adenosine receptors (ARs), in particular A1 (A1R) and A2A (A2AR) receptors. Interestingly, A2AR levels are upregulated in cortical and hippocampal regions in several pathological condi...

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Literature Corpus work: b280d6c0-d7c5-5a89-b18e-bb670b4ea554
DOI: 10.21203/rs.3.rs-4791082/v1

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