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Potential Astrocytic Receptors and Transporters in the Pathogenesis of Alzheimer’s Disease

1 Feb 2019

Abstract excerpt

Alzheimer's disease (AD) is the most common cause of dementia and is characterized by the progressive loss of memory and cognition in the aging population. However, the etiology of and therapies for AD remain far from understood. Astrocytes, the most abundant neuroglia in the brain, have recently aroused substantial concern due to their involvement in synaptotoxicity, amyloidosis, neuroinflammation, and oxidative...

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PMID: 30741675
DOI: 10.3233/jad-181084

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