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Chronic activation of astrocytic G <sub>q</sub> GPCR signaling has causal effects on visual LTP formation: implications for neurodegenerative diseases

2024-04-20

Abstract excerpt

Astrocytes are the most abundant glial cells in the central nervous system and interact with other cell types, including neurons and microglia, via G q protein-coupled receptors (G q GPCRs) present on their surface. Astrocytic G q GPCR activation induces Ca 2+ release from internal stores, leading to intracellular Ca 2+ elevations. There is emerging evidence supporting that astrocytic G q GPCR Ca 2+ elevat...

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Literature Corpus work
c8a57a26-77da-5483-a791-db0c02164f95
DOI
10.1101/2024.04.16.589763
Open publication

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Chronic activation of astrocytic G <sub>q</sub> GPCR signaling has causal effects on visual LTP formation: implications for neurodegenerative diseasesDOI 10.1101/2024.04.16.589763
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