Article

PAPγ associates with PAXT nuclear exosome to control the abundance of PROMPT ncRNAs

2023-10-04

Abstract excerpt

Pervasive transcription of the human genome generates an abundance of RNAs that must be processed and degraded. The nuclear RNA exosome is the main RNA degradation machinery in the nucleus. However, nuclear exosome must be recruited to its substrates by targeting complexes, such as NEXT or PAXT. By proteomic analysis, we have identified additional subunits of PAXT, including many orthologs of MTREC found in S. po...

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Literature Corpus work: b280a0e9-099f-5620-aea7-19584e20efe1
DOI: 10.1101/2023.10.04.560886

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