Article

A heterochromatin-specific RNA export pathway facilitates piRNA production

2019-04-02

Abstract excerpt

PIWI-interacting RNAs (piRNAs) guide transposon silencing in animals. The 22-30nt piRNAs are processed in the cytoplasm from long non-coding RNAs. How piRNA precursors, which often lack RNA processing hallmarks of export-competent transcripts, achieve nuclear export is unknown. Here, we uncover the RNA export pathway specific for piRNA precursors in the Drosophila germline. This pathway requires Nxf3-Nxt1, a vari...

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Literature Corpus work: c2eddedc-d388-563c-830b-5396dfae02f2
DOI: 10.1101/596171

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