Article

TREND-DB – A Transcriptome-wide Atlas of the Dynamic Landscape of Alternative Polyadenylation

2020-08-04

Abstract excerpt

Alternative polyadenylation (APA) profoundly expands the transcriptome complexity. Perturbations of APA can disrupt biological processes, ultimately resulting in devastating disorders. A major challenge in identifying mechanisms and consequences of APA (and its perturbations) lies in the complexity of RNA 3’end processing, involving poorly conserved RNA motifs and multi-component complexes consisting of far more t...

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Literature Corpus work: bde99b42-d305-50f4-a204-6cfd82798bc6
DOI: 10.1101/2020.08.04.235804

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