Article

Genomic codes governing enhancer RNA fate

2024-10-31

Abstract excerpt

Long-read sequencing has transformed transcriptome profiling, yet capturing full-length, non-polyadenylated transcripts like enhancer RNAs (eRNAs) remains challenging. Here, we introduce CFC-seq, combining cap-trapping and in vitro poly(A)-tailing to sequence poly(A) and non-poly(A) RNAs with precise transcription start site. Paired with our assembler, SALA, we identified 39,425 novel transcriptional units, inclu...

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Literature Corpus work: a166e01d-2288-5e77-a99b-71c1c7f3ca17
DOI: 10.1101/2024.10.31.620483

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