Article

Peroxisome proliferator-activated receptor alpha is essential factor in enhanced macrophage immune function induced by angiotensin converting enzyme

2024-04-22

Abstract excerpt

<title>Abstract</title> <p>An upregulation of angiotensin-converting enzyme (ACE) expression strengthens the immune activity of myeloid lineage cells as a natural functional regulation mechanism in our immunity. ACE10/10 mice, possessing increased ACE expression in macrophages, exhibit enhanced anti-tumor immunity and anti-bactericidal effects compared to those of wild type (WT) mice, while the detailed molecular...

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Literature Corpus work: b265b2ff-b6a0-5423-ae0a-60cbbee6e0a2
DOI: 10.21203/rs.3.rs-4255086/v1

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