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Article

Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2013

Lenglet Sébastien, Thomas Aurélien, Soehnlein Oliver, Montecucco Fabrizio, Burger Fabienne, Pelli Graziano, Galan Katia, Cravatt Benjamin, Staub Christian, Steffens Sabine

Abstract excerpt

OBJECTIVE: Endocannabinoid levels are elevated in human and mouse atherosclerosis, but their causal role is not well understood. Therefore, we studied the involvement of fatty acid amide hydrolase (FAAH) deficiency, the major enzyme responsible for endocannabinoid anandamide degradation, in atherosclerotic plaque vulnerability. METHODS AND RESULTS: We assessed atherosclerosis in apolipoprotein E-deficient...

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Source

Identifiers

PMID: 23241405
DOI: 10.1161/ATVBAHA.112.300275

Genes

FAAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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