Article

LXR nuclear receptors prompt a pro-inflammatory gene and functional profile in human macrophages

2021-02-15

Abstract excerpt

<title>Abstract</title> <p>Liver X Receptors (LXR) control cholesterol metabolism and exert anti-inflammatory actions in activated macrophages. However, their contribution to human macrophage polarization in the absence of pathogenic stimuli remains unclear. In fact, the LXR pathway has been reported to be significantly enriched in pro-inflammatory synovial macrophages from rheumatoid arthritis patients as well a...

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Literature Corpus work: 830386ad-c305-5be1-a45b-07d1db25fd1b
DOI: 10.21203/rs.3.rs-169946/v1

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