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Article

Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia.

Immunobiology - 1 Jan 2021

Haydar Dalia, Gonzalez Rene, Garvy Beth A, Garneau-Tsodikova Sylvie, Thamban Chandrika Nishad, Bocklage Therese J, Feola David J

Abstract excerpt

Regulatory properties of macrophages associated with alternative activation serve to limit the exaggerated inflammatory response during pneumonia caused by Pseudomonas aeruginosa infection. Arginase-1 is an important effector of these macrophages believed to play an essential role in decreasing injury and promoting repair. We investigated the role of arginase-1 in the control of inflammatory immune responses to...

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Identifiers

PMID: 33278710
DOI: 10.1016/j.imbio.2020.152034
PMCID: PMC7855574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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