Article
Genes that escape from X inactivation.
Human genetics - 1 Aug 2011
Berletch Joel B, Yang Fan, Xu Jun, Carrel Laura, Disteche Christine M
Abstract excerpt
To achieve a balanced gene expression dosage between males (XY) and females (XX), mammals have evolved a compensatory mechanism to randomly inactivate one of the female X chromosomes. Despite this chromosome-wide silencing, a number of genes escape X inactivation: in women about 15% of X-linked g...
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