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Article

Escape from X inactivation varies in mouse tissues.

PLoS genetics - 1 Mar 2015

Berletch Joel B, Ma Wenxiu, Yang Fan, Shendure Jay, Noble William S, Disteche Christine M, Deng Xinxian

Abstract excerpt

X chromosome inactivation (XCI) silences most genes on one X chromosome in female mammals, but some genes escape XCI. To identify escape genes in vivo and to explore molecular mechanisms that regulate this process we analyzed the allele-specific expression and chromatin structure of X-linked genes in mouse tissues and cells with skewed XCI and distinguishable alleles based on single nucleotide polymorphisms....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25785854
DOI: 10.1371/journal.pgen.1005079
PMCID: PMC4364777

Genes

CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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