Article

Scuphr: A probabilistic framework for cell lineage tree reconstruction

2018-06-29

Abstract excerpt

Cell lineage tree reconstruction methods are developed for various tasks, such as investigating the development, differentiation, and cancer progression. Single-cell sequencing technologies enable more thorough analysis with higher resolution. We present Scuphr, a distance-based cell lineage tree reconstruction method using bulk and single-cell DNA sequencing data from healthy tissues. Common challenges of single-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b17bddf4-4892-588e-ba9d-691a42572963
DOI: 10.1101/357442

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Scuphr: A probabilistic framework for cell lineage tree reconstructionDOI 10.1101/357442Read

A probabilistic framework for cellular lineage reconstruction using single-cell 5-hydroxymethylcytosine sequencingSemantic proximity Read

Retrospective cell lineage reconstruction in Humans using short tandem repeatsSemantic proximity Read

Comparing algorithms that reconstruct cell lineage trees utilizing information on microsatellite mutations.Semantic proximity Read

Overcoming Expressional Drop-outs in Lineage Reconstruction from Single-Cell RNA-Sequencing Data.Semantic proximity Read

Efficient reconstruction of cell lineage trees for cell ancestry and cancer.Semantic proximity Read

Assessing the Performance of Methods for Cell Clustering from Single-cell DNA Sequencing DataSemantic proximity Read

Accuracy of Answers to Cell Lineage Questions Depends on Single-Cell Genomics Data Quality and Quantity.Semantic proximity Read

Probabilistic cell lineage inference from mitochondrial mutationsSemantic proximity Read

Tracking Somatic Mutations for Lineage Reconstruction.Semantic proximity Read

ScisTree2 enables large-scale inference of cell lineage trees and genotype calling using efficient local search.Semantic proximity Read

Retrospective cell lineage reconstruction in humans by using short tandem repeats.Semantic proximity Read

scMitoMut for calling mitochondrial lineage–related mutations in single cellsSemantic proximity Read