Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ScisTree2 enables large-scale inference of cell lineage trees and genotype calling using efficient local search.

Genome research - 3 Dec 2025

Zhang Haotian, Zhang Yiming, Gao Teng, Wu Yufeng

Abstract excerpt

In a multicellular organism, cell lineages share a common evolutionary history. Knowing this history can facilitate the study of development, aging, and cancer. Cell lineage trees represent the evolutionary history of cells sampled from an organism. Recent developments in single-cell sequencing have greatly facilitated the inference of cell lineage trees. However, single-cell data are sparse and noisy, and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Cell Lineage
Share to Computational Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Models, Genetic

Share to Single-Cell Analysis

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 40903391
DOI: 10.1101/gr.280542.125
PMCID: PMC12667710

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ScisTree2 enables large-scale inference of cell lineage trees and genotype calling using efficient local search.PMID 40903391Read ↗

Accurate and efficient cell lineage tree inference from noisy single cell data: the maximum likelihood perfect phylogeny approachSemantic proximity Read ↗

CellPhy: accurate and fast probabilistic inference of single-cell phylogenies from scDNA-seq data.Semantic proximity Read ↗

Inference of Single-Cell Phylogenies from Lineage Tracing DataSemantic proximity Read ↗

Inference of single-cell phylogenies from lineage tracing data using Cassiopeia.Semantic proximity Read ↗

Scuphr: A probabilistic framework for cell lineage tree reconstructionSemantic proximity Read ↗

MiTo: tracing the phenotypic evolution of somatic cell lineages via mitochondrial single-cell multi-omicsSemantic proximity Read ↗

Probabilistic cell lineage inference from mitochondrial mutationsSemantic proximity Read ↗

SIEVE: joint inference of single-nucleotide variants and cell phylogeny from single-cell DNA sequencing dataSemantic proximity Read ↗

PhyloSOLID: Robust phylogeny reconstruction from single-cell data despite inherent error and sparsitySemantic proximity Read ↗

Mapping single-cell-resolution cell phylogeny reveals cell population dynamics during organ development.Semantic proximity Read ↗

Dynamic programming algorithms for fast and accurate cell lineage tree reconstruction from CRISPR-based lineage tracing dataSemantic proximity Read ↗

MiTo: tracing the phenotypic evolution of somatic cell lineages via mitochondrial single-cell multi-omics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.